Amorphophallus commutatus

Yadu Nandan Dey, Shankhajit De, and Ajoy Kumar Ghosh, Evaluation of analgesic activity of methanolic extract of Amorphophallus paeoniifolius tuber by tail flick and acetic acid induced writhing response method, International Journal of Pharma and Bioscience.

The diarrhoea was clinically apparent in all the animals of control group, for the next 4 hour 30 min after administration of castor oil. So the extract has agonistic activity with benzodiazepine receptor, which might similar to that of diazepam. The reaction was stopped by the addition of 2.

The tubers are anodyne, antiinflammatory, antihaemorrhoidal, haemostatic, expectorant, carminative, digestive, appetizer, stomachic, anthelmintic, liver tonic, aphrodisiac, emmenagogue, rejuvenating and tonic. Breifly in a test tube; 0.

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The reaction mixture 1. Higher absorbance of the reaction mixture indicated greater reductive potential. All groups received intraperitoneal injection maximum 1 ml as per ethical norms. Lower absorbance of the reaction mixture indicated higher free radical scavenging activity.

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Both the doses reduced the total number of faeces as well as total number of wet faeces in test animals. Corresponding Author: P. Key words: Amorphophallus paeoniifolius, antioxidant activity, antitumor activity, analgesic activity, antidiarrhoeal activity, CNS depressant activity, phytochemical constituents, cytotoxicity. They are traditionally used in arthralgia, elephantiasis, tumors, inflammations, hemorrhoids, hemorrhages, vomiting, cough, bronchitis, asthma, anorexia, dyspepsia, flatulence, colic, constipation,helminthiasis hepatopathy, spleenopathy, amenorrhea, dysmenorrhoea, seminal weakness, fatigue, anemia and general debility. Key words: Amorphophallus paeoniifolius, antioxidant activity, antitumor activity, analgesic activity, antidiarrhoeal activity, CNS depressant activity, phytochemical constituents, cytotoxicity. The tuber is reported to have antiprotease activity, CNS depressant activity, analgesic activity, and cytotoxic activity2. Briefly, the reaction mixture contained 0. All the experimental animals were killed by cervical decapitation after the experimental period. The diarrhoea was clinically apparent in all the animals of control group, for the next 4 hour 30 min after administration of castor oil. So, further research has to be carried out to overcome the shortcomings of the drugs and to relieve the suffering humanity and to obtain superior therapeutically active drugs from this source. Phenobarbitone and diazepam are well known CNS depressant drugs and also showed CNS depressant activity in a dose-dependant manner. Group V: Diazepam 0. The reaction was stopped by the addition of 2.

From the dose response curve of each drug, the effective doses were calculated.

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IAS: Amorphophallus commutatus